Blumenfeld-Katzir, T., Michaelson, D.M. and Yaniv, A.(2014) ApoE genotype Effect on Brain Plasticity Studied with MRI (submitted)
Boehm-Cagan, A., Michaelson, D.M. (2014) Reversal of apoE4-driven brain pathology and behavioral deficits by bexarotene. J. Neurosci. 34(21): 7293-7301.
Michaelson, D.M. (2014) ApoE4: the most prevalent yet understudied risk factor for Alzheimer’s disease. Alzheimer’s and Dementia, Sept. 2014.
Gilat-Frenkel, M., Bohem-Cagan, A., Liraz, O., Xian, X., Herz, J., Michaelson D.M. (2014) Involvement of the apoER2 and Lrp1 receptors in mediating the pathological effects of apoE4 in vivo. Curr. Alzheimer Res. 11(6): 549-557.
Shiran Salomon-Zimri, Ori Liraz), and Daniel M. Michaelson (2014). Behavioral testing affects the phenotypic expression of apoE3 and apoE4 in targeted replacement mice and reduces the differences between them.In Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring Alzhiemer's and dementia: (in press)
Salomon-Zimri,S., Boehm-Cagan,A., Liraz,O., and. Michaelson, D.M.,(2014). Hippocampal- related cognitive impairments in young apoE4-targeted replacement mice. Neurodegener. Dis.13(2-3); 86-92.
Liraz, O., Boehm, A., Michaelson, D.M. (2013) Aβ, tau and synaptic pathology are induced by apoE4 at a young age. Molecular Neurodegeneration . 2013 May 17;8:16
Zepa, L., Frenkel, M., Belinson ,H., Kayed, R., Masliah, E., and Michaeslon, D.M (2011) ApoE4-driven accumulation of intraneuronal oligomerized Aβ42 following activation of the amyloid cascade in vivo is mediated by a gain of function. Int. J. Alzheimer Disease. Feb (2011) 79170).
Kariv-Inbal, Z., Yacobson, S., Berkez, R., Peter, M., Janaky, T., Lutjohanm D., Broersen, L.M., Hartman,, T., Michaelson, D.M. (2011) The isoform specific pathological effects of apoE4 in vivo are prevented by a fish oil (DHA) diet and modified by cholesterol. J. Alzheimer. Disease. 28(3), 667-683.
Belinson, H., Kariv-Inbal, Z., Kayed, R., Masliah, E., Michaeslon, D.M. (2010) . ApoE4 drives the oligomerization of Abeta in vivo following activation of the amyloid cascade resulting in neurodegeneration . J. Alzheimer Disease 22(3), 959-970.
Belinson, H., and Michaelson, D.M. (2009) Pathological synergism between amyloid-beta and apolipoprotein E4 – the most prevalent yet understudied genetic risk factor for Alzheimer's disease. J. Alzheimers Dis. 17(3), 469-481.
Belinson, H., Lev, D., Masliah, E., and Michaelson D.M .( 2008) Activation of the amyloid cascade in apoE4 tansgenic mice induces lysosomal activation and neurodegeneration resulting in marked cognitive deficits. J. Neuroscie.28(11), 4690-701.
Dolev, I. And Michaelson, D.M. (2004) A nontransgenic mouse model shows inducible amyloid-beta pep deposition and elucidates the role of apolipoprotein E in the amyloid cascade. Proc. Natl. Acad. Sci. U.S.A. 101(38):13909-13914.