Guido Sessa received his B.Sc. in Agriculture from The Hebrew University of Jerusalem, and M.Sc. and Ph.D. in plant genetics from the Weizmann Institute of Science. From 1997 to 2000, he carried out a postdoctoral training at Purdue University and Cornell University. Since 2000, he is a faculty member at the Dept. of Molecular Biology and Ecology of Plants at Tel Aviv University.
Prof. Guido Sessa
The main interest of the Sessa laboratory is to study of molecular mechanisms that govern plant immunity and susceptibility to bacterial pathogens. On the plant side, we use molecular biology, functional genomics and proteomics approaches to dissect recognition events and signal transduction pathways that mediate immunity. On the bacterial side, we apply genetic and biochemical strategies to unveil the mode of action of bacterial virulence factors that manipulate host functions. Our investigation has a direct impact on agriculture by providing targets and biotechnological strategies for the development of disease control against economically important pathogens.
Savidor, A., D. Teper, K-H. Gartemann, R. Eichenlaub, L. Chalupowicz, S. Manulis-Sasson, I. Barash, G. Sessa (2014). Clavibacter michiganensis subsp. michiganensis Vatr1 and Vatr2 transcriptional regulators are required for virulence in tomato. Molecular Plant-Microbe Interactions 27: 1035-1047.
Teper, D., D. Salomon, S. Sunitha, J-G. Kim, M. B. Mudgett and G. Sessa (2014). Xanthomonas euvesicatoria type III effector XopQ interacts with tomato and pepper 14-3-3 isoforms to suppress effector-triggered immunity. Plant J. 77: 297-309.
Molecular Plant Immunity, pp. 277 (2013). Editor: G. Sessa. Wiley-Blackwell, a John Wiley & Sons Inc. Publications.
Gruetter, C., S. Sreeramulu, G. Sessa, D. Rauh (2013). Structural characterization of the RLCK family member BSK8: a pseudokinase with an unprecedented architecture. J. Mol. Biol. 425: 4455-4467.
Sreeramulu, S., Y. Mostizky, S. Sunitha, H. Nahum, E. Shani, D. Salomon, L. Ben Hayun, C. Gruetter, D. Rauh, N. Ori, and G. Sessa (2013). BSKs are partially redundant positive regulators of brassinosteroid signaling in Arabidopsis. Plant J. 74: 905-919.
Salomon, D., E. Bosis, D. Dar, I. Nachman, G. Sessa (2012). Expression of Pseudomonas syringae type III effectors in yeast under stress conditions reveals that HopX1 attenuates activation of the high osmolarity glycerol MAP kinase pathway. Microbiology 158: 2859-2869.
Savidor, A., D. Teper, K-H. Gartemann, R. Eichenlaub, L. Chalupowicz, S. Manulis-Sasson, I. Barash, H. Tews, K. Mayer, R. Giannone, R. Hettich, and G. Sessa (2012). The Clavibacter michiganensis subsp. michiganensis–tomato interactome reveals perception of pathogen by host and suggests mechanisms of infection. J. Proteome Res. 11: 736-750.
Bosis, E., Salomon, D. and G. Sessa (2011). A simple yeast-based strategy to identify host cellular processes targeted by bacterial effector proteins. PLoS ONE 6, e27698.
Melech-Bonfil S. and G. Sessa (2011). The SlMKK2 and SlMPK2 genes play a role in tomato disease resistance to Xanthomonas campestris pv. vesicatoria. Plant Signaling and Behavior 6: 154-156.
Salomon, D., D. Dar, S. Sreeramulu and G. Sessa (2011). Expression of Xanthomonas campestris pv. vesicatoria type III effectors in yeast affects cell growth and viability. Molecular Plant-Microbe Interactions 24: 305-314.
Melech-Bonfil S. and G. Sessa. Tomato MAPKKKε is a positive regulator of cell-death signaling networks associated with plant immunity (2010). Plant J. 64: 379-391.
Salomon, D. and G. Sessa (2010). Identification of growth inhibition phenotypes induced by expression of bacterial type III effectors in yeast. J. Visual. Exp. http://www.jove.com/index/details.stp?id=1865, doi: 10.3791/1865.
Salomon, D., A. Bonshtien and G. Sessa (2009). A chemical-genetic approach for functional analysis of plant protein kinases. Plant Signaling & Behavior 4: 645-647.
Salomon, D., A. Bonshtien, M. Mayrose, C. Zhang, K.M. Shokat and G. Sessa (2009). Bypassing kinase activity of the tomato Pto resistance protein with small-molecule ligands. J. Biol. Chem. 284: 15289-15298.
Balaji, V., M. Mayrose, O. Sherf, J. Jacob-Hirsch, R. Eichenlaub, N. Iraki, S. Manulis-Sasson, G. Rechavi, I. Barash and G. Sessa (2008). Tomato transcriptional changes in response to Clavibacter michiganensis subsp. michiganensis reveal a role for ethylene in disease development. Plant Physiol. 4: 1797-1809.