List of publications – March 2022

Prof. Eran Bacharch, Prof. Avigdor Eldar, Prof. Marcelo Ehrlich  & Prof. Adi Stern

Inferring protein function in an emerging virus: detection of the nucleoprotein in Tilapia Lake Virus.

Abu Rass R, Kustin T, Zamostiano R, Smorodinsky N, Ben Meir D, Feder D, Mishra N, Lipkin WI, Eldar A, Ehrlich M, Stern A, Bacharach E. J Virol. 2022 Feb 2: JVI0175721.

doi: 10.1128/JVI.01757-21. Online ahead of print. PMID: 35107373

 

Prof. Adit Ben-Baruch

Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes.

Erlichman N, Baram T, Meshel T, Morein D, Da'adoosh B, Ben-Baruch A. Cancers (Basel). 2022 Feb 18;14(4):1042.

doi: 10.3390/cancers14041042. PMID: 35205789 Free PMC article.

 

Prof. Marcelo Ehrlich

Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways.

Szilágyi SS, Amsalem-Zafran AR, Shapira KE, Ehrlich M, Henis YI. BMC Biol. 2022 Feb 18;20(1):50.

doi: 10.1186/s12915-022-01252-z. PMID: 35177083 Free PMC article.

 

Prof. Avigdor Eldar

Dormant phages communicate via arbitrium to control exit from lysogeny.

Aframian N, Omer Bendori S, Kabel S, Guler P, Stokar-Avihail A, Manor E, Msaeed K, Lipsman V, Grinberg I, Mahagna A, Eldar A. Nat Microbiol. 2022 Jan;7(1):145-153.

doi: 10.1038/s41564-021-01008-5. Epub 2021 Dec 9. PMID: 34887546

 

Prof. Tal Dvir

A universal, multimodal cell-based biosensing platform for optimal intracellular action potential recording.

Xu D, Fang J, Yadid M, Zhang M, Wang H, Xia Q, Li H, Cao N, Dvir T, Hu N. Biosens Bioelectron. 2022 Feb 25;206:114122.

doi: 10.1016/j.bios.2022.114122. Online ahead of print. PMID: 35245868

 

Bioengineering approaches to treat the failing heart: from cell biology to 3D printing.

Yadid M, Oved H, Silberman E, Dvir T. Nat Rev Cardiol. 2022 Feb;19(2):83-99.

doi: 10.1038/s41569-021-00603-7. Epub 2021 Aug 27. PMID: 34453134 Review.

 

Chondroitin sulfate-AuNRs electroactive scaffolds for on-demand release of biofactors.

Malki M, Shapira A, Dvir T. J Nanobiotechnology. 2022 Jan 31;20(1):59.

doi: 10.1186/s12951-022-01261-8. PMID: 35101034 Free PMC article.

 

Prof. Tal Dvir & Prof. Irit Gat-Viks

Regenerating the Injured Spinal Cord at the Chronic Phase by Engineered iPSCs-Derived 3D Neuronal Networks.

Wertheim L, Edri R, Goldshmit Y, Kagan T, Noor N, Ruban A, Shapira A, Gat-Viks I, Assaf Y, Dvir T. Adv Sci (Weinh). 2022 Feb 7:e2105694.

doi: 10.1002/advs.202105694. Online ahead of print. PMID: 35128819

 

Prof. Ehud Gazit

Guest Molecule-Mediated Energy Harvesting in a Conformationally Sensitive Peptide-Metal Organic Framework.

Chen Y, Guerin S, Yuan H, O'Donnell J, Xue B, Cazade PA, Haq EU, Shimon LJW, Rencus-Lazar S, Tofail SAM, Cao Y, Thompson D, Yang R, Gazit E. J Am Chem Soc. 2022 Mar 2;144(8):3468-3476.

doi: 10.1021/jacs.1c11750. Epub 2022 Jan 24. PMID: 35073071

 

Peptide Coassembly to Enhance Piezoelectricity for Energy Harvesting.

Yuan H, Han P, Tao Z, Xue B, Guo Y, Levy D, Hu W, Wang Y, Cao Y, Gazit E, Yang R. ACS Appl Mater Interfaces. 2022 Feb 9;14(5):6538-6546.

doi: 10.1021/acsami.1c20146. Epub 2022 Jan 28. PMID: 35089003

 

Prof. Uri Gophna

Socioeconomic disparities and household crowding in association with the fecal microbiome of school-age children.

Lapidot Y, Reshef L, Maya M, Cohen D, Gophna U, Muhsen K. NPJ Biofilms Microbiomes. 2022 Mar 3;8(1):10.

doi: 10.1038/s41522-022-00271-6. PMID: 35241676

 

Reply to Antibiotic Use Patterns in the Management of Chronic Pouchitis.

Bar N, Dubinsky V, Gophna U, Dotan I. Inflamm Bowel Dis. 2022 Feb 21:izab352.

doi: 10.1093/ibd/izab352. Online ahead of print. PMID: 35188203 No abstract available.

 

Safety and Tolerability, Dose-Escalating, Double-Blind Trial of Oral Mannitol in Parkinson's Disease.

Linetsky E, Abd Elhadi S, Bauer M, Gallant A, Namnah M, Weiss S, Segal D, Sharon R, Arkadir D. Front Neurol. 2022 Jan 3;12:716126.

doi: 10.3389/fneur.2021.716126. eCollection 2021. PMID: 35046880 Free PMC article.

 

Microbiome-related aspects of locust density-dependent phase transition.

Lavy O, Lewin-Epstein O, Bendett Y, Gophna U, Gefen E, Hadany L, Ayali A. Environ Microbiol. 2022 Jan;24(1):507-516.

doi: 10.1111/1462-2920.15883. Epub 2022 Jan 24. PMID: 35068041

 

Prof. Ehud Gazit & Prof. Daniel Segal

The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity.

Abu-Hussien M, Viswanathan GK, Simhaev L, Paul A, Engel H, Gazit E, Segal D. Int J Biol Macromol. 2022 Jan 6;201:182-192.

doi: 10.1016/j.ijbiomac.2021.12.192. Online ahead of print. PMID: 34998884

 

Prof. Martin Kupiec

Metabolic remodeling maintains a reducing environment for rapid activation of the yeast DNA replication checkpoint.

Li L, Wang J, Yang Z, Zhao Y, Jiang H, Jiang L, Hou W, Ye R, He Q, Kupiec M, Luke B, Cao Q, Qi Z, Li Z, Lou H. EMBO J. 2022 Jan 14:e108290.

doi: 10.15252/embj.2021108290. Online ahead of print. PMID: 35028974

 

TOR complex 2 contributes to regulation of gene expression via inhibiting Gcn5 recruitment to subtelomeric and DNA replication stress genes.

Cohen A, Pataki E, Kupiec M, Weisman R. PLoS Genet. 2022 Feb 14;18(2):e1010061.

doi: 10.1371/journal.pgen.1010061. eCollection 2022 Feb. PMID: 35157728 Free PMC article.

 

Dr. Vered Padler-Karavani

The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration.

Senage T, Paul A, Le Tourneau T, Fellah-Hebia I, Vadori M, Bashir S, Galiñanes M, Bottio T, Gerosa G, Evangelista A, Badano LP, Nassi A, Costa C, Cesare G, Manji RA, Cueff de Monchy C, Piriou N, Capoulade R, Serfaty JM, Guimbretière G, Dantan E, Ruiz-Majoral A, Coste du Fou G, Leviatan Ben-Arye S, Govani L, Yehuda S, Bachar Abramovitch S, Amon R, Reuven EM, Atiya-Nasagi Y, Yu H, Iop L, Casós K, Kuguel SG, Blasco-Lucas A, Permanyer E, Sbraga F, Llatjós R, Moreno-Gonzalez G, Sánchez-Martínez M, Breimer ME, Holgersson J, Teneberg S, Pascual-Gilabert M, Nonell-Canals A, Takeuchi Y, Chen X, Mañez R, Roussel JC, Soulillou JP, Cozzi E, Padler-Karavani V. Nat Med. 2022 Feb;28(2):283-294.

doi: 10.1038/s41591-022-01682-w. Epub 2022 Feb 17. PMID: 35177855

 

Prof. Dan Peer

Delivery strategies of RNA therapeutics to leukocytes.

Tarab-Ravski D, Stotsky-Oterin L, Peer D. J Control Release. 2022 Feb;342:362-371.

doi: 10.1016/j.jconrel.2022.01.016. Epub 2022 Jan 15. PMID: 35041904

 

Principles for designing an optimal mRNA lipid nanoparticle vaccine.

Kon E, Elia U, Peer D. Curr Opin Biotechnol. 2022 Feb;73:329-336.

doi: 10.1016/j.copbio.2021.09.016. Epub 2021 Oct 26. PMID: 34715546 Free PMC article. Review.

 

Dual-Targeted Lipid Nanotherapeutic Boost for Chemo-Immunotherapy of Cancer.

Yong SB, Ramishetti S, Goldsmith M, Diesendruck Y, Hazan-Halevy I, Chatterjee S, Somu Naidu G, Ezra A, Peer D. Adv Mater. 2022 Jan 19:e2106350.

doi: 10.1002/adma.202106350. Online ahead of print. PMID: 35044699

 

Prof. Tal Pupko

Effectidor: an automated machine-learning based web server for the prediction of type-III secretion system effectors.

Wagner N, Avram O, Gold-Binshtok D, Zerah B, Teper D, Pupko T. Bioinformatics. 2022 Feb 14:btac087.

doi: 10.1093/bioinformatics/btac087. Online ahead of print. PMID: 35157036

 

Prof. Aldema Sas-Chen

A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit.

Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A, Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren AJ, Minczuk M. Nat Commun. 2022 Feb 17;13(1):929.

doi: 10.1038/s41467-022-28503-5. PMID: 35177605 Free PMC article.

 

Prof. Gil Segal

The Legionella genus core effectors display functional conservation among orthologs by themselves or combined with an accessory protein.

Wexler M, Zusman T, Linsky M, Lifshitz Z, Segal G. Curr Res Microb Sci. 2022 Jan 8;3:100105.

doi: 10.1016/j.crmicr.2022.100105. eCollection 2022. PMID: 35059677 Free PMC article.

 

Prof. Beka Solomon

Inhibition of CXCR4/CXCL12 signaling: a translational perspective for Alzheimer's disease treatment.

Gavriel Y, Rabinovich-Nikitin I, Solomon B. Neural Regen Res. 2022 Jan;17(1):108-109.

doi: 10.4103/1673-5374.314303. PMID: 34100443 Free PMC article. No abstract available.