Publications

2024

 

Chronic and acute exposure to rotenone reveals distinct Parkinson's disease-related phenotypes in human iPSC-derived peripheral neurons. Mahmood Ali Saleh, Fatima Amer-Sarsour, Metsada Pasmanik-Chor, Hila Kobo, Gad D. Vatine, and Avraham Ashkenazi. Free Radical Biology and Medicine, 213, 164-173, 2024 (Full Text)

 

2023

 

Calcium regulation of the Arabidopsis Na+/K+ transporter HKT1;1 improves seed germination under salt stress. Ancy E.J. Chandran, Aliza Finkler, Tom Hait, Yvonne Kiere, Sivan David, Metsada Pasmanik-Chor and Doron Shkolnik. Plant Physiology, accepted, doi: 10.1093/plphys/kiad651. Online ahead of print 2023 (Abstract)(Full Text)

 

Heterogeneity in the Metastatic Microenvironment: JunB-Expressing Microglia Cells as Potential Drivers of Melanoma Brain Metastasis Progression. Orit Adir, Orit Sagi-Assif, Tsipi Meshel, Shlomit Ben-Menachem, Metsada Pasmanik-Chor, Dave S.B. Hoon, Isaac P. Witz, Sivan Izraely. Cancers, 15(20):4979. https://doi.org/10.3390/cancers15204979. 2023 (Abstract)(Full Text)

 

Oculopharyngeal muscular dystrophy mutations link the RNA-binding protein HNRNPQ to autophagosome biogenesis. Hasan Ishtayeh, Margarita Galves, Tania T. Barnatan, Yevgeny Berdichevsky, Fatima Amer-Sarsour, Metsada Pasmanik-Chor, Itzhak Braverman, Sergiu C. Blumen, Avraham Ashkenazi. Aging Cell, Volume 22, Issue 10, e13949. https://doi.org/10.1111/acel.13949, 2023 (Abstract)(Full Text)

 

A heterodimer of α and β hemoglobin chains functions as an innate anticancer agent. Chelladurai Maharrish, Xu Dan, Izraely Sivan, Ben-Menachem Shlomit, Bengaiev Roman, Sagi-Assif Orit, Yuan Weirong, Pasmanik-Chor Metsada, Hoon Dave, Lu Wuyuan, Witz Isaac. Int J Cancer, 154(3):561-572. doi: 10.1002/ijc.34702. 2023 (Abstract)(Full Text)

 

Antiviral activity of glucosylceramide synthase inhibitors in alphavirus infection of the central nervous system. Roy Avraham, Sharon Melamed, Hagit Achdout, Noam Erez, Ofir Israeli, Moria Barlev-Gross, Metsada Pasmanik-Chor, Nir Paran, Tomer Israely, Einat B Vitner. Brain Commun. 25;5(3):fcad086.  doi: 10.1093/braincomms/fcad086. eCollection 2023 (Abstract)(Full Text)

 

The Vicious Cycle of Melanoma-Microglia Crosstalk: Inter-Melanoma Variations in the Brain-Metastasis-Promoting IL-6/JAK/STAT3 Signaling Pathway. Sivan Izraely, Shlomit Ben-Menachem, Sapir Malka, Orit Sagi-Assif, Matias A. Bustos, Orit Adir, Tsipi Meshel, Maharrish Chelladurai, Suyeon Ryu, Romela. Ramos, Metsada Pasmanik-Chor, Dave S. B. Hoon and Isaac P. Witz. Cells, 12; 1513. https://doi.org/10.3390/cells12111513, 2023 (Abstract)(Full Text)

 

A Tumor Microenvironment-Driven Network Regulated by STAT3 and p65 Negatively Controls the Enrichment of Cancer Stem Cells in Human HR+/HER2− Breast Cancer. Ben-Yaakov, H. Meshel, T. Pasmanik-Chor, M. Körner, C. Ben-Baruch, A. Cancers, 15(8), 2255. https://doi.org/10.3390/cancers15082255, 2023 (Abstract)(Full Text)

 

Tomato receptor-like cytoplasmic kinase Fir1 is involved in flagellin signaling and regulates pre-invasion immunity. Sobol G, Majhi BB, Pasmanik-Chor M, Zhang N, Roberts HM, Martin GB, Sessa G. Plant Physiology: 192: 565–581, 2023 (Abstract)(Full Text)

 

Serine peptidases and increased amounts of soluble proteins contribute to heat priming of the plant pathogenic fungus Botrytis cinerea. Mingzhe Zhang, Naomi Trushina, Tabea Lang, Matthias Hahn, Metsada Pasmanik-Chor, Amir Sharon. bioRxiv 2023.03.23.534054; doi: https://doi.org/10.1101/2023.03.23.534054, 2023 (Abstract)(Full Text)

2022

 

Epigenetic aging waves: Artificial intelligence detects clustering of switch points in DNA methylation rate in defined sex-dependent age periods. Elad Segev, Tamar Shahal, Thomas Konstantinovsky, Yonit Marcus, Gabi Shefer, Yuval Ebenstein, Metsada Pasmanik-Chor, Naftali Stern. bioRxiv preprint doi: https://doi.org/10.1101/2022.10.02.510495 ; 2022 (Abstract)(Full Text)

 

Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis. Itay Moshkovits,  Ayelet Kaminitz,  Debby Reuveni,  Metsada Pasmanik-Chor,  Eli Brazowski,  Alexander Mildner,  Achim Leutz,  Ehud Zigmond. Immunity, Inflammation and Disease, Volume10, Issue11, e728, 2022 (Abstract)(Full Text)

 

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Proposed Therapy in a Rat Model of Cerebral Small Vessel Disease. Reut Guy, Shay Herman, Hadar Benyamini, Tali Ben-Zur, Hila Kobo, Metsada Pasmanik-Chor, Dafna Yaacobi, Eric Barel, Chana Yagil, Yoram Yagil, Daniel Offen. Int J Mol Sci. 23;23(19):11211. doi: 10.3390/ijms231911211, 2022 (Abstract)(Full Text)

 

Tomato brassinosteroid-signaling kinase Bsk830 is a component of flagellin signaling that regulates pre-invasion immunity. Guy Sobol, Bharat Bhusan Majhi, Metsada Pasmanik-Chor, Ning Zhang, Holly M. Roberts, Gregory B. Martin, Guido Sessa. bioRxiv preprint, doi: https://doi.org/10.1101/2022.06.01.494411 (Abstract)(Full Text)

 

Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage. Einat Bigelman,                  Metsada Pasmanik-Chor, Bareket Dassa, Maxim Itkin, Sergey Malitsky, Orly Dorot, Edward Pichinuk, Smadar Levin-Zaidman,          Nili Dezorella, Atan Gross, Anastasia Abashidze, Yuval Kleinberg, Gad Keren, Michal Entin-Meer. bioRxiv; doi: https://doi.org/10.1101/2022.05.17.492275, 2022 (Abstract)(Full Text) 

 

Deconvolution of the epigenetic age discloses distinct inter-personal variability in epigenetic aging patterns. Tamar Shahal, Elad Segev, Thomas Konstantinovsky, Yonit Marcus, Gabi Shefer, Metsada Pasmanik-Chor, Assaf Buch, Yuval Ebenstein, Paul Zimmet, Naftali Stern. Epigenetics & Chromatin 15(1);9, doi: https://doi.org/10.1186/s13072-022-00441-y, 2022 (Abstract)(Full Text)

 

Genomic alterations drive metastases formation in pancreatic ductal adenocarcinoma cancer: deciphering the role of CDKN2A and CDKN2B in mediating liver tropism. Shani Journo, Anat Klein Goldberg, Ethan Sokol, Lotem Zinger, Metsada Pasmanik-Chor, Boris Sarvin, Dor Simkin, Sivan Fucks, Tomer Shlomi, Ido Wolf and Tami Rubinek. Oncogene. doi: 10.1038/s41388-022-02184-2, 2022. (Abstract)(Full Text)

 

2021

MicroRNA 132-3p is Upregulated in Laron Syndrome Patients and Controls Longevity Gene Expression. Danielle Yaron-Saminsky, Karthik Nagaraj, Rive Sarfstein, Zvi Laron, Metsada Pasmanik-Chor and Haim Werner. Int. J. Mol. Sci. Nov 1;22(21):11861. doi: 10.3390/ijms222111861; https://www.mdpi.com/1422-0067/22/21/11861/htm#, 2021 (Abstract)(Full Text)

 

Autophagy is induced and modulated by cholesterol depletionthrough transcription of autophagy-related genes andattenuation offlux. Keren E. Shapira, Guy Shapira, Eran Schmukler, Metsada Pasmanik-Chor, Noam Shomron, Ronit Pinkas-Kramarski, Yoav I. Henis and Marcelo Ehrlich. Cell Death Discovery 7: 320; https://doi.org/10.1038/s41420-021-00718-3, 2021 (Abstract)(Full Text)

 

Novel ADNP syndrome mice reveal dramatic sex-specific peripheral gene expression with brain synaptic and Tau pathologies. Gidon Karmon, Shlomo Sragovich, Gal Hacohen-Kleiman, Inbar Ben-Horin-Hazak, Petr Kasparek, Björn Schuster, Radislav Sedlacek, Metsada Pasmanik-Chor, Paschalis Theotokis, Olga Touloumi, Sofia Zoidou, Linxuan Huang, Pei You Wu, Roy Shi, Oxana Kapitansky, Alexandra Lobyntseva, Eliezer Giladi, Guy Shapira, Noam Shomron, Stefan Bereswill, Markus M.Heimesaat, Nikolaus Grigoriadis, R. Anne McKinney, Moran Rubinstein, llanaGozes. Biological Psychiatry; https://doi.org/10.1016/j.biopsych.2021.09.018, 2021 (Abstract)(Full Text)

 

Fibroblasts from the oral masticatory and lining mucosa have different gene expression profiles and proliferation rates. Liron Kabakov, Carlos E. Nemcovsky, Metsada Plasmanik-Chor, Haya Meir, Daniel Z. Bar, Evgeny Weinberg. J Clin Periodontol. 48(10):1393-1401. doi: 10.1111/jcpe.13532, 2021 (Abstract)(Full Text)

 

De novo transcriptome characterization of Iris atropurpurea (the Royal Iris) and phylogenetic analysis of MADS-box and R2R3-MYB gene families. Yamit Bar-Lev, Esther Senden, Metsada Pasmanik-Chor, Yuval Sapir. Sci Rep 11, 16246; https://doi.org/10.1038/s41598-021-95085-5, 2021 (Abstract)(Full Text)

 

Continuous inflammatory stimulation leads via metabolic plasticity to a pro-metastatic phenotype in triple-negative breast cancer cells. Dina Morein, Linor Rubinstein-Achiasaf, Hadar Brayer, Orly Dorot, Edward Pichinuk, Hagar Ben-Yaakov, Tsipi Meshel, Metsada Pasmanik-Chor, Adit Ben-Baruch. Cells, 10(6):1356. doi: 10.3390/cells10061356, 2021 (Abstract)(Full Text)

 

COPII collar defines the boundary between ER and ER exit site and does not coat cargo containers. Olga Shomron, Inbar Nevo-Yassaf, Tamar Aviad, Yakey Yaffe, Eitan Erez Zehavi, Anna Dukhovny, Eran Perlson, Ilya Brodsky, Adva Yeheskel, Metsada Pasmanik-Chor, Anna Mironov, Galina V. Beznoussenko, Alexander A. Moronov, Ella H. Salan, George H. Patterson, Yoni Yonemura, Mara Sannai, Christoph Kaether, Koret Hirschberg. J Cell Biol (2021) 220 (6):e201907224; https://doi.org/10.1083/jcb.201907224, 2021 (Abstract)(Full Text)

Ribosomal proteins as distinct "passengers" of microvesicles: new semantics in myeloma and mesenchymal stem cells' communication. Dabbah M, Lishner M, Jarchowsky-Dolberg O, Tartakover Matalon S, Brin Y, Pasmanik-Chor M, Drucker L. Transl Res. S1931-5244(21)00084-0. doi: 10.1016/j.trsl.2021.04.002, 2021 (Abstract)(Full Text)

 

The uncovered function of the Drosophila GBA1a-encoded protein. Or Cabasso, Sumit Paul, Gali Maor, Metsada Pasmanik-Chor, Wouter Kallemeijn, Johannes Aerts, Mia Horowitz. Cells, 10(3), 630, 2021 (Abstract)(Full Text)

 

Biological Perspectives of RNA-Sequencing Experimental Design. Metsada Pasmanik-Chor, In: Shomron, N. (eds) Deep Sequencing Data Analysis. Methods in Molecular Biology, vol 2243: 327-337. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1103-6_17; 2021. PMID: 33606266, 2021 (Abstract)(Full Text)

 

2020

The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the malignant phenotype of melanoma cells - a case of inter-tumor heterogeneity. Sivan Izraeli, Shlomit Ben-Menachem, Orit Sagi-Assif, Tsipi Meshel, Sapir Malka, Alona Telerman, Matias A. Bustos, Romela Irena Ramos, Metsada Pasmanik-Chor, Dave S. B. Hoon, Issac Witz. Molecular Oncology, 15(5): 1376-1390, 2020. https://doi.org/10.1002/1878-0261.12872 (Abstract)(Full Text)

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Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody. Lena Cohen, Irit Sagi, Einat Bigelman, Inna Solomonov, Anna Aloshin, Jeremy Ben-Shoshan, Metsada Pasmanik-Chor, Zach Rozenbaum, Gad Keren, and Michal Entin-Meer. PLoS ONE 15(4): e0231202 10.1371/journal.pone.0231202. (Abstract)(Full Text)

Correction: PLoS One. 15(10): e0241419. Published online 2020. doi: 10.1371/journal.pone.0241419. 2020

 

STAT3 isoforms differentially affect ACE2 expression: A potential target for COVID-19 therapy. Inbal Shamir, Mor Abutbul-Amitai, Haya Abbas-Egbariya, Metsada Pasmanik-Chor, Gideon Paret and Yael Nevo-Caspi. J. Cell Mol. Med. 2020. doi: 10.1111/jcmm.15838. Epub ahead of print. PMID: 32949179 (Abstract)(Full Text)

Systems Analysis of Insulin and IGF1 Receptors Networks in Breast Cancer Cells Identifies Commonalities and Divergences in Expression Patterns. Rive Sarfstein, Adva Yeheskel, Tali Sinai-Livne, Metsada Pasmanik-Chor and Haim Werner. Front. Endocrinol., 11:435, 2020. https://doi.org/10.3389/fendo.2020.00435 (Abstract)(Full Text)

 

Inter-Tumor Heterogeneity: Melanomas Respond Differently to GM-CSF-Mediated Activation. Adi Moshe, Sivan Izraely, Orit Sagi Assif, Sapir Malka, Shlomit Ben-Menachem, Tsipi Meshel, Metsada Pasmanik-Chor, Dave S.B. Hoon, Isaac P. Witz. Cells, vol. 9(7): E1683, ​https://doi.org/10.3390/cells9071683 ; 2020 (Abstract)(Full Text)

 

R269C variant of ESR1: high prevalence and differential function in a subset of pancreatic cancers. Tomer Boldes, Keren Merenbakh-Lamin, Shani Journo, Eliya Shachar, Doron Lipson, Adva Yeheskel, Metsada Pasmanik-Chor, Tami Rubinek, Ido Wolf. BMC Cancer, 20:531, 2020 (Abstract)(Full Text)

 

​Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients. Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner and Raanan Berger. Oncotarget, 11(17):1515-1530, 2020 (Abstract)(Full Text)

 

Profiling and Bioinformatics Analyses Reveal Chronic Lymphocytic Leukemia Cells Share a Unique Circular RNA Expression Pattern. Oshrat Raz, Galit Granot, Metsada Pasmanik-Chor, Pia Raanani, Uri Rozovski. Experimental Hematology, 2020. doi: https://doi.org/10.1016/j.exphem.2020.04.001 (Abstract)(Full Text)

 

Micro-RNA Expression Patterns Predict Metastatic Spread in Solid Pseudopapillary Neoplasms of the Pancreas. Shmuel Jaffe Cohen, Michail Papoulas, Nadine Graubardt, Esther Ovdat, Shelly Loewenstein, Juliane Kania-Almog, Metsada Pasmanik-Chor, Eli Brazowski, Emanuela Cagnano, Ido Nachmany, Guy Lahat, Joseph M. Klausner and Nir Lubezky. Front. Oncol., 2020. https://doi.org/10.3389/fonc.2020.00328 (Abstract)(Full Text)

 

VIP/PACAP-Based Drug Development: The ADNP/NAP-Derived Mirror Peptides SKIP and D-SKIP Exhibit Distinctive in vivo and in silico Effects. Sragovich S, Amram N, Yeheskel A, Gozes I. Front Cell Neurosci.: 13:589, 2020 (Abstract)(Full Text)

 

Reduced culture temperature attenuates oxidative stress and inflammatory response facilitating expansion and differentiation of adipose-derived stem cells. Gal Tirza, Inna Solodeev, Meirav Sela, Ilanit Greenberg, Metsada Pasmanik-Chor, Eyal Gur and Nir Shani. Stem Cell Research & Therapy 11(1): 35, 2020 (Abstract)(Full Text)

 

Multiple myeloma BM-MSCs increase the tumorigenicity of MM cells via transfer of VLA4 enriched microvesicles.  Mahmoud Dabbah,  Osnat Jarchowsky-Dolberg,  Oshrat Attar-Schneider,  Shelly Tartakover-Matalon,  Metsada Pasmanik-Chor,  Liat Drucker,  Michael Lishner.  Carcinogenesis, https://doi.org/10.1093/carcin/bgz169, 2020  (Abstract)(Full Text)

 

2019

 

De novo Transcriptome Characterization of Royal Iris (Iris section Oncocyclus) and Identification of Flower Development Genes. Bar-Lev Yamit, Senden Esther, Pasmanik-Chor Metsada and Sapir Yuval. doi: https://doi.org/10.1101/680363, 2019 (Full Text)

 

Signal-induced PARP1-Erk synergism mediates IEG expression. Cohen-Armon M, Yeheskel A, Pascal JM. Signal Transduct Target Ther. 12;4:8, 2019 (Abstract)(Full Text)

 

MicroRNAs affect complement regulator expression and mitochondrial activity to modulate cell resistance to complement-dependent cytotoxicity. Yaron Hillman, Mariya Mardamshina,  Metsada Pasmanik-Chor,  Lea Ziporen,  Tamar Geiger,  Noam Shomron  and  Zvi Fishelson.  Cancer Immunology research, DOI: 10.1158/2326-6066.CIR-18-0818, 2019 (Abstract)(Full Text)

 

Drosophila melanogaster Mutated in its GBA1b Ortholog Recapitulates Neuronopathic Gaucher Disease. Or Cabasso, Sumit Paul, Orly Dorot, Gali Maor, Olga Krivoruk, Metsada Pasmanik-Chor, Mina Mirzaian, Maria Ferraz, Johannes Aerts and Mia Horowitz. J. of Clinical Medicine, 8:1420, 2019 (Abstract)(Full Text)

 

NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis. Nour Ershaid, Yoray Sharon, Hila Schwartz, Yael Raz, Ophir Shani, Noam Cohen, Lea Monteran, Leonor Leider-Trejo, Muhammad Yassin, Amir Ben-Shmuel, Motti Gerlic, Adit Ben-Baruch, Metsada Pasmanik-Chor, RN Apte, and Neta Erez. Nature Communications, 26;10(1):4375. doi:10.1038/s41467-019-12370-8, 2019 (Abstract)(Full Text)

 

Uncoating of COPII from ER exit site membranes precedes cargo accumulation and membrane fission.  Olga Shomron,  Inbar Nevo-Yassaf,  Tamar Aviad,  Yakey Yaffe,  Eitan Erez Zahavi,  Anna Dukhovny,  Eran Perlson,  Ilya Brodsky,  Adva Yeheskel,  Metsada Pasmanik-Chor,  Anna Mironov,  Galina V.  Beznoussenko,  Alexander A.  Mironov,  Ella H.  Sklan, George H.  Patterson,  Yoji Yonemura,  Christoph Kaether,  Koret Hirschberg.  bioRxiv, doi: https://doi.org/10.1101/727107; 2019 (Abstract)(Full Text)

 

Genome-Wide Profiling of Laron Syndrome Patients Identifies Novel Cancer Protection Pathways.  Haim Werner, Lena Lapkina-Gendler, Laris Achlaug, Karthik Nagaraj, Lina Somri, Danielle Yaron-Saminsky, Metsada Pasmanik-Chor, Rive Sarfstein, Zvi Laron and Shoshana Yakar.  Cells, 8(6): 596  https://doi.org/10.3390/cells8060596 (registering DOI), 2019 (Abstract)(Full Text)

 

MicroRNA profiling of pancreatic ductal adenocarcinoma (PDAC) reveals signature expression related to lymph node metastasis. Moran Lemberger, Shelly Loewenstein, Nir Lubezky, Eran Nizri, Metsada Pasmanik-Chor, Eli Barazovsky, Joseph M. Klausner and Guy Lahat. Oncotarget, 10(27): 2644-2656, 2019 (Abstract)(Full Text)

 

Calmodulin-binding transcription activator 6: a key regulator of Na+ homeostasis during germination. Doron Shkolnik, Aliza Finkler, Metsada Pasmanik-Chor, and Hillel Fromm. Plant Physiology,  Vol. 180: 1101–1118; https://doi.org/10.1104/pp.19.00119, 2019 (Abstract)(Full Text)

 

​Ligand binding domain activating mutations of ESR1 rewire cellular metabolism of breast cancer cells. Lotem Zinger, Keren Merenbakh-Lamin, Anat Klein Goldberg, Adi Elazar, Shani Journo, Tomer Boldes, Metsada Pasmanik-Chor, Avishay Spitzer, Tamar Rubinek, and Ido Wolf. Clinical Cancer Research, 25(9): 2900-2914, DOI: 10.1158/1078-0432.CCR-18-1505, 2019 (Abstract)(Full Text)

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The Metastatic Microenvironment: Melanoma‐Microglia Cross‐Talk Promotes the Malignant Phenotype of Melanoma Cells. Sivan Izraely, Shlomit Ben‐Menachem, Orit Sagi‐Assif, Alona Telerman, Inna Zubrilov, Ofir Ashkenazi, Tsipi Meshel, Shelly Maman, Javier I.J. Orozco, Matthew P. Salomon, Diego M. Marzese, Metsada Pasmanik‐Chor, Eli Pikarsky, Marcelo Ehrlich, Dave S.B. Hoon, Isaac P. Witz. Int. J. of Cancer. 144(4):802-817, 2019 (Abstract)(Full Text)

 

Risk gene-set and pathways in 22q11.2 deletion-related schizophrenia: a genealogical molecular approach. Michaelovsky E, Carmel M, Frisch A, Salmon-Divon M, Pasmanik-Chor M, Weizman A, Gothelf D. Translational Psychiatry, 9:15, 2019 (Abstract)(Full Text)

 

GIP regulates inflammation and body weight by restraining myeloid cell-derived 100A8/A9. Fernanda Mantelmacher, Isabel Zvibel, Keren Cohen, Alona Epshtein, Metsada Pasmanik-Chor, Thomas Vogl, Yael Kuperman, Shai Weiss, Daniel Drucker, Chen Varol, and Sigal Fishman. Nature Metabolism, 1, 58-69, 2019 (Full Text)

2018

 

Genomic analysis of the original Elberg Brucella melitensis Rev.1 vaccine strain reveals insights into virulence attenuation. Salmon-Divon M, Yeheskel A, Kornspan D. Virulence. 2018;9(1):1436-1448 (Abstract)(Full Text)

 

Placenta‐conditioned extracellular matrix (ECM) activates breast cancer cell survival mechanisms: A key for future distant metastases. Oded Komemi,  Gali Epstein Shochet, Meir Pomeranz, Ami Fishman, Metsada Pasmanik‐Chor, Liat Drucker, Shelly Tartakover Matalon, Michael Lishner. International J. of Cancer, 144(7):1633-1644, 2018 (Abstract)(Full Text)

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Activity-dependent neuroprotective protein deficiency models synaptic and developmental phenotypes of autism-like syndrome. Hacohen-Kleiman G, Sragovich S, Karmon G, Gao AYL, Grigg I, Pasmanik-Chor M, Le A, Korenková V, McKinney RA, Gozes I. J. Clin. Invest. 128(11): 4956-4969, 2018 (Abstract)(Full Text)

 

Klotho suppresses colorectal cancer through modulation of the unfolded protein response. Tammi Arbel Rubinstein, Shiri Shahmoon, Ehud Zigmond, Tal Etan, Keren Merenbakh-Lamin, Metsada Pasmanik-Chor, Gil Har Zahav, Iris Barshack, Gilad W. Vainer, Nir Skalka, Rina Rosin-Arbesfeld, Chen Varol, Tami Rubinek, Ido Wolf. Oncogene, doi: 10.1038/s41388-018-0489-4. [Epub ahead of print] 2018 (Abstract)(Full Text)

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Mechano-redox control of integrin de-adhesion. Passam F, Chiu J, Ju L, Pijning A, Jahan Z, Mor-Cohen R, Yeheskel A, Kolšek K, Thärichen L, Aponte-Santamaría C, Gräter F, Hogg PJ. Elife. Jun 22;7, 2018 (Abstract)(Full Text)

 

Increase in Processing Factors Is Involved in Skewed MicroRNA Expression in Patients with Ulcerative Colitis Who Develop Small Intestine Inflammation after Pouch Surgery. Sherman Horev H, Rabinowitz KM, Elad H, Barkan R, Ben-Shachar S, Pasmanik Chor M, Dotan I. Inflamm Bowel Dis. 24(5): 1045-1054, 2018 (Abstract)

 

Bosutinib, Dasatinib, Imatinib, Nilotinib and Ponatinib differentially affect the vascular molecular pathways and functionality of human endothelial cells. Ayala Gover-Proaktor, Galit Granot, Metsada Pasmanik-Chor, Oren Pasvolsky, Saar Shapira, Oshrat Raz, Pia Raanani and Avi Leader. Leukemia and Lymphoma 9: 1-11, 2018 (Abstract)(Full Text)

 

GEView (Gene Expression View) tool for intuitive and high accessible visualization of expression data for non-programmer biologists. Libi Hertzberg, Assif Yitzhaky and Metsada Pasmanik-Chor. International Journal of Knowledge Discovery in Bioinformatics Volume 8, Issue 1, January-June 2018 (Full Text)

 

Genome-wide analyses identify filamin-A (FLNA) as a novel downstream target for insulin and IGF1 action. Daniel Aizen, Metsada Pasmanik-Chor, Rive Sarfstein, Zvi Laron, Ilan Bruchim, Haim Werner. Frontiers in Endocrinology, section Cancer Endocrinology, 20;9: 105, 2018 (Abstract)(Full Text)

 

Identification of thioredoxin-interacting protein (TXNIP) as a novel downstream target for IGF1 action. Karthik Nagaraj, Lena Lapkina-Gendler, Rive Sarfstein, David Gurwitz, Metsada Pasmanik-Chor, Zvi Laron, Shoshana Yakar, Haim Werner. PNAS, Early Edition, Karthik Nagaraj, doi: 10.1073/pnas.1715930115, 2018 (Abstract)(Full Text)

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2017

 

Simulation and visualization of multiple KEGG pathways using BioNSi. Adva Yeheskel, Adam Reiter, Metsada Pasmanik-Chor, Amir Rubinstein.  F1000Research, 6: 2120, 2017. (Abstract)(Full Text)

 

Food restriction followed by refeeding with a casein- or whey-based diet differentially affects the gut microbiota of pre-pubertal male rats. Majdi Masarwi, Hadas Isaac Solnik, Moshe Phillip, Sima Yaron, Raanan Shamir, Metsada Pasmanik-Chor, and Galia Gat-Yablonski. J Nutr Biochem. 14; 51:27-39. doi: 10.1016/j.jnutbio.2017.08.014, 2017. (Abstract)(Full Text)

 

Beta palmitate improves bone length and quality during catch-up growth in young rats. Meytal Bar-Maisels, Yankel Gabet, Raanan Shamir, Sahar Hiram-Bab, Metsada Pasmanik-Chor, Moshe Phillip, Fabiana Bar-Yosheph, Galia Gat-Yablonski. Nutrients, 9(7): 764; doi:10.3390/nu9070764, 2017. (Abstract)(Full Text)

 

Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing. Reichman Hadar, Moshkovits Itay, Itan Michal, Pasmanik-Chor Metsada, Vogl Thomas, Roth Johannes & Munitz Ariel. Scientific Reports 7, Article number: 7117, doi:10.1038/s41598-017-07738-z, 2017. (Abstract)(Full Text)

 

CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production. Rozenberg P, Reichman H, Zab-Bar I, Itan M, Pasmanik-Chor M, Bouffi C, Qimron U, Bachelet I, Fulkerson PC, Rothenberg ME, Munitz A. Sci Rep. 19; 7(1):5922. doi: 10.1038/s41598-017-06397-4, 2017. (Abstract)(Full Text)

 

ANGPTL4 Promotes the Progression of Cutaneous Melanoma to Brain Metastasis. Sivan Izraely, Shlomit Ben-Menachem, Orit Sagi-Assif, Tsipi Meshel, Diego M. Marzese, Shuichi Ohe, Inna Zubrilov, Metsada Pasmanik-Chor, Dave S.B. Hoon, Isaac P. Witz. Oncotarget, 8: 75778-75796. doi: 10.18632/oncotarget.19018. 2017. (Abstract)(Full Text).

 

Unique Cellular Interactions between Pancreatic Cancer Cells and the Omentum. Valerya Feygenzon, Shelly Loewenstein, Nir Lubezky, Metsada Pasmanic-Chor, Osnat Sher,  Joseph M Klausner, Guy Lahat. PLoS One, 20;12(6): e0179862. doi: 10.1371, 2017. (Abstract)(Full Text)

 

Ly6Chi monocytes and their macrophage descendants regulate neutrophil function and clearance in acetaminophen-induced liver injury. Nadine Graubardt, Milena Vugman, Odelia Mouhadeb, Gabriele Caliari, Metsada Pasmanik-Chor, Debby Reuveni, Ehud Zigmond, Eli Brazowski, Eyal David, Louise Chappell-Maor, Steffen Jung, Chen Varol. Frontiers in Immunology, section Molecular Innate Immunity, 8: 626, doi: 10.3389/fimmu.2017.00626, 2017. (Abstract)(Full Text)

 

Differential gene expression and transport functionality in the bundle sheath versus mesophyll – a potential role in leaf mineral homeostasis. Noa Wigoda, Metsada Pasmanik-Chor, Tianyuan Yang, Ling Yu, Menachem Moshelion, Nava Moran. J Exp Bot. 1;68(12): 3179-3190, 2017. (Abstract)(Full Text)

 

ALS Along the Axons – Expression of Coding and Noncoding RNA Differs in Axons of ALS models. Rotem N., Magen I., Ionescu A., Gershoni-Emek N., Altman T., Gradus T., Pasmanik-Chor M., Willis DE., Ben-Dov IZ., Horenstein E., Perlson E. Sci. Rep. 7: 44500, doi:10.1038/srep44500, 2017. (Abstract)(Full Text)

 

Glucose-dependent insulinotropic polypeptide (GIP) receptor deficiency leads to impaired BM hematopoiesis. Fernanda Dana Mantelmacher, Sigal Fishman, Keren Cohen, Metsada Pasmanik Chor, Yuichiro Yamada, Isabel Zvibel, Chen Varol. The Journal of Immunology 198(8): 3089-3098, 2017. (Abstract)(Full Text)

 

Premature Primary Tooth Eruption in Cognitive/Motor Delayed ADNP-Mutated Children. I. Gozes, A. Van Dijck, G. Hacohen Kleiman, I. Grigg, G. Karmon, E. Giladi, M. Eger, Y. Gabet, M. Pasmanik-Chor, E. Cappuyns, O. Elpeleg, R.F. Kooy, S. Bedrosian Sermone. Translational Psychiatry, 7(2):e1043, 2017. (Abstract)(Full Text)

 

2016​

 

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An allosteric disulfide bond is involved in enhanced activation of factor XI by protein disulfide isomerase. Zucker M, Seligsohn U, Yeheskel A, Mor-Cohen R. J Thromb Haemost. 14: 2202-2211, 2016. (Abstract)(Full Text)

 

MicroRNAs Expression in the Ileal Pouch of Patients with Ulcerative Colitis Is Robustly Up-Regulated and Correlates with Disease Phenotypes. Ben-Shachar S, Yanai H, Sherman Horev H, Elad H, Baram L, Issakov O, Tulchinsky H, Pasmanik-Chor M, Shomron N, Dotan I. PLoS One. 11(8):e0159956. doi: 10.1371/journal.pone. 0159956, 2016 (Abstract)(Full Text)

 

RGS2 expression predicts amyloid-β sensitivity, MCI and Alzheimer’s disease: genome-wide transcriptomic profiling and bioinformatics data mining. Adva Hadar, Elena Milanesi, Alessio Squassina, Paola Niola, Caterina Chillotti, Metsada Pasmanik-Chor, Orly Yaron, Pavel Martásek, Moshe Rehavi, Daphna Weisglass-Volkov, Noam Shomron, Illana Gozes and David Gurwitz. Translational Psychiatry, 6(10):e909. doi: 10.1038/tp.2016.179, 2016. (Abstract)(Full text)

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A PARP1-ERK2 synergism is required for the induction of LTP.  Visochek L, Grigoryan G, Kalal A, Milshtein-Parush H, Gazit N, Slutsky I, Yeheskel A, Shainberg A, Castiel A, Seger R, Langelier MF, Dantzer F, Pascal JM, Segal M, Cohen-Armon M. Nature Scientific Reports, 6:24950, 2016. (Abstract)(Full Text)

 

Identification of signaling pathways associated with cancer protection in Laron syndrome. Lena Lapkina, Itai Rotem, Metsada Pasmanik-Chor, David Gurwitz, Rive Sarfstein, Zvi Laron and Haim Werner. Endocrine-Related Cancer, 23(5): 399-410, 2016. (Abstract)(Full Text) 

 

Fluid consumption and taste novelty determines transcription temporal dynamics in the gustatory cortex. Inberg S., Jacob E., Elkobi A., Edry E., Rappaport A., Simpson TI., Armstrong JD., Shomron N., Pasmanik-Chor M., Rosenblum K. Molecular Brain, 9: 13, 2016. (Abstract)(Full Text)

 

First trimester human placenta prevents breast cancer cell attachment to the matrix: the role of extracellular matrix. Epstein Shochet G, Drucker L, Pomeranz M, Fishman A, Pasmanik-Chor M, Tartakover-Matalon S, Lishner M. Molecular Carcinogenesis, 56(1): 62-74, 2016. (Abstract)(Full Text)

 

Intercellular transfer of small RNAs from astrocytes to lung tumor cells induces resistance to chemotherapy. Assaf Menachem, Victoria Makovski, Or Bodner, Metsada Pasmanik-Chor, Reuven Stein, Noam Shomron and Yoel Kloog. Oncotarget, 7(11): 12489-12504, 2016. (Abstract)(Full Text)

 

Sexual Divergence in Microtubule Function: The Novel Intranasal Microtubule Targeting SKIP Normalizes Axonal Transport and Enhances Memory. Noy Amram, Gal Hacohen-Kleiman, Shlomo Sragovich, Anna Malishkevich, Jeny Katz, Olga Touloumi, Roza Lagoudaki, Nikolaos C. Grigoriadis, Eliezer Giladi, Adva Yeheskel, Metsada Pasmanik-Chor, Yan Jouroukhin and Illana Gozes. Molecular Psychiatry, 21(10): 1467-1476, 2016. (Abstract)(Full Text)

 

Maternal Diet Enriched with α-Linolenic or Saturated Fatty Acids Differentially Regulates Gene Expression in the Liver of Mouse Offspring. Alicia Leikin-Frenkel, Limor Shomonov-Wagner, Ana Juknat, Metsada Pasmanik-Chor. Journal of Nutrigenetics and Nutrigenomics, 8:185–194, 2016. (Abstract)(Full Text)

 

2015

 

A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. Caspi M, Firsow A, Rajkumar R, Skalka N, Moshkovitz I, Munitz A, Pasmanik-Chor M, Greif H, Megido D, Kariv R, Rosenberg DW, Rosin-Arbesfeld R. J Mol Med (Berl), 94(4): 469-482, 2015. (Abstract)(Full Text)

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Risperidone and NAP protect cognition and normalize gene expression in a schizophrenia mouse model. Vaisburd S, Shemer Z, Yeheskel A, Giladi E, Gozes I. Sci Rep. 10; 5: 16300, 2015. (Abstract)(Full Text)

 

BRCA1/2 mutations perturb telomere biology: characterization of structural and functional abnormalities in vitro and in vivo. Orit Uziel, Rinat Yerushalmi, Lital Zuriano, Shaden Naser, Einat Beery, Jardena Nordenberg, Ido Lubin, Yonatan Adel, Daniel Shepshelovich, Hagai Yavin, Shlomit Pery, Shulamit Rizel, Metsada Pasmanik-Chor, Dan Frumkin and Meir Lahav. Oncotarget, 7(3): 2433-2454, 2015. (Abstract)(Full Text)

 

Expression of Quinone Reductase-2 in the Cortex is a Muscarinic Acetylcholine Receptor-Dependent Memory Consolidation Constraint. Akiva Rappaport, Eyal Jacob, Vijendra Sharma, Sharon Inberg, Alina Elkobi, Hadile Ounallah-Saad, Metsada Pasmanik-Chor, Efrat Edry, and Kobi Rosenblum. Journal of Neuroscience 35(47): 15568-15581, 2015. (Abstract)(Full Text)

 

Tumor Suppressor Activity of Klotho in Breast Cancer is Revealed by Structure-function Analysis. Ligumsky H, Rubinek T, Merenbakh-Lamin K, Yeheskel A, Sertchook R, Shahmoon S, Aviel-Ronen S, Wolf I. Mol Cancer Res. 13(10): 1398-407, 2015. (Abstract)(Full Text)

 

A protective role for IL-13 receptor |[alpha]| 1 in bleomycin-induced pulmonary injury and repair. D Karo-Atar, A Bordowitz, O Wand, M Pasmanik-Chor, I E Fernandez, M Itan, R Frenkel, D R Herbert, F D Finkelman, O Eickelberg & A Munitz. Mucosal Immunology advance online publication, 2015. doi:10.1038/mi.2015.56, 2015. (Abstract)(Full Text)

 

Inhibition of ZEB1 expression induces redifferentiation of adult human beta cells expanded in vitro. Elad Sintov, Gili Nathan, Sarah Knoller, Metsada Pasmanik-Chor, Holger A. Russ & Shimon Efrat. Nature Sci. Rep. 5, 13024; doi: 10.1038/srep13024, 2015. (Abstract)(Full Text)

 

MicroRNAs of the RPE are essential for RPE differentiation and photoreceptor maturation. Reut Ohana, Benjamin Weiman-Kelman, Shaul Raviv, Ernst R Tamm, Metsada Pasmanik-Chor, Ariel Rinon, Devir Netanely, Ron Shamir, Arie S Salomon, and Ruth Ashery-Padan, Development: 142(14):2487-98, 2015. (Abstract)(Full Text)

 

The myelin proteolipid Plasmolipin, forms oligomers and induces liquid ordered membranes in the Golgi apparatus. Yakey Yaffe, Ilan Hagger, Inbar Nevo Yassaf, Jeanne Shepshelovitch, Ella H Sklan, Yechiel Elkabetz, Adva Yeheskel, Metsada Pasmanik-Chor, Carola Benzing, Alexander Macmillan, Katharina Gaus, Yael Eshed-Eisenbach, Elior Peles, and Koret Hirschberg., Journal of Cell Science: 1;128(13):2293-302, 2015. (Abstract)(Full Text)

 

RBM28, a protein deficient in ANE syndrome, regulates hair follicle growth via miR-203 and p63. Emily Warshauer, Liat Samuelov, Ofer Sarig, Dan Vodo, Albrecht Bindereif, Moien Kanaan, Uri Gat, Dana Fuchs-Telem, Noam Shomron, Luba Farberov, Metsada Pasmanik-Chor, Gil Nardini, Eyal Winkler, Benjamin Meilik, Isabelle Petit, Daniel Aberdam, Ralf Paus, Eli Sprecher, Janna Nousbeck. Experimental Dermatology, 24: 618–622, 2015. (Abstract)(Full Text)

 

Homozygous MED25 Mutation Implicated in Eye-Intellectual Disability Syndrome. Lina Basel-Vanagaite, Pola Smirin-Yosef, Jenna Lee Essakow, Shay Tzur, Irina Lagovsky, Idit Maya, Metsada Pasmanik-Chor, Adva Yeheskel, Osnat Konen, Naama Orenstein, Monika Weisz Hubshman, Valerie Drasinover, Nurit Magal, Gaby Peretz Amit, Yael Zalzstein, Avraham Zeharia, Mordechai Shohat, Didier Monté, Mali Salmon-Divon, Doron M. Behar. Human Genetics: 134(6):577-87, 2015. (Abstract)(Full Text)

 

Vemurafenib resistance selects for highly malignant brain and lung-metastasizing melanoma cells. Zubrilov I, Sagi-Assif O, Izraely S, Meshel T, Ben-Menahem S, Ginat R, Pasmanik-Chor M, Nahmias C, Couraud PO, Hoon DS, Witz IP. Cancer Lett. 28; 361(1):86-96, 2015. (Abstract)(Full Text)

 

Restoration of miR-424 suppresses BCR–ABL activity and sensitizes CML cells to imatinib treatment. Oshrat Hershkovitz-Rokah, Shira Modai, Metsada Pasmanik-Chor, Amos Toren, Noam Shomron, Pia Raanani, Ofer Shpilberg, Galit Granot. Cancer Letters 360(2): 245–256, 2015. (Abstract)(Full Text)

 

First trimester human placental factors induce breast cancer cell autophagy. Epstein Shochet Gali, Tartakover Matalon Shelly, Drucker Liat, Pasmanik-Chor Metsada, Pomeranz Meir, Fishman Ami, Lishner Michael. Breast Cancer Research and Treatment 149(3): 645-54, 2015. (Abstract)(Full Text)

 

MiR-30e induces apoptosis and sensitizes K562 cells to imatinib treatment via regulation of the BCR-ABL protein. Hershkovitz-Rokah O, Modai S, Pasmanik-Chor M, Toren A, Shomron N, Raanani P, Shpilberg O, Granot G., Cancer Lett. 356(2 Pt B): 597-605, 2015. (Abstract)(Full Text)

 

EIF4E and EIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling. Oshrat Attar-Schneider, Metsada Pasmanik-Chor, Shelly Tartakover-Matalon, Liat Drucker and Michael Lishner. Oncotarget, 6(6): 4315-4329, 2015. (Abstract)(Full Text)

 

2014

 

Placenta-breast cancer cell interactions promote cancer cell epithelial mesenchymal transition via TGFβ/JNK pathway. Epstein Shochet G, Tartakover-Matalon S, Drucker L, Pasmanik-Chor M, Pomeranz M, Fishman A, Lishner M., Clin Exp Metastasis 31(8):961-75, 2014. (Abstract)(Full Text)

 

MicroRNA profiling reveals opposing expression patterns for miR-511 in alternatively and classically activated macrophages. Karo-Atar D, Itan M, Pasmanik-Chor M, Munitz A., J Asthma 18:1-9, 2014. (Abstract)(Full Text)

 

Activity-Dependent Neuroprotective Protein (ADNP): A Case Study for Highly Conserved Chordata-Specific Genes Shaping the Brain and Mutated in Cancer. Gozes I, Yeheskel A, Pasmanik-Chor M, J Alzheimers Dis. 1;45(1):57-73, 2014. (Abstract)(Full Text)

 

Epithelial-to-Mesenchymal Transition (EMT) in Intraductal Papillary Mucinous Neoplasm (IPMN) is Associated with High Tumor Grade and Adverse Outcomes. Guy Lahat, Nir Lubezky, Shelly Loewenstein, Eran Nizri, Sarah Gan, Metsada Pasmanik-Chor, Luciile Hayman, Eli Barazowsky, Menahem Ben-Haim, Joseph M. Klausner., Ann Surg Oncol. Suppl 4:S750-72014. (Abstract)(Full Text)

 

Gene expression alterations in ulcerative colitis patients after restorative proctocolectomy extend to the small bowel proximal to the pouch. Henit Yanai, Shay Ben-Shachar, Liran Baram, Hofit Elad, Gilad Gitstein, Eli Brazowski, Hagit Tulchinsky, Metsada Pasmanik-Chor, Iris Dotan. Gut, doi:10.1136/gutjnl-2014-307387, 2014. (Abstract)(Full Text)

 

Infiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury. Ehud Zigmond, Shany Samia-Grinberg, Metsada Pasmanik-Chor, Eli Brazowski, Oren Shibolet, Zamir Halpern and Chen Varol. Journal of Immunology 193(1): 344-353, 2014. (Abstract)(Full Text)

 

Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB.. Alonso H, Kleifeld O, Yeheskel A, Ong PC, Liu YC, Stok JE, De Voss JJ, Roujeinikova A. Biochem J. 460(2):283-93, 2014. (Abstract)(Full Text)

 

Hierarchical Partitioning of Metazoan Protein Conservation Profiles Provides New Functional Insights. Jonathan Witztum, Erez Persi, David Horn, Metsada Pasmanik-Chor, Benny Chor. PLOS one 9(3):e90282, 2014. (Abstract)(Full Text)

 

Association between variants of 5-hydroxytryptamine receptor 3C (HTR3C) and chemotherapy-induced symptoms in women receiving adjuvant treatment for breast cancer. Pud D, Har-Zahav G, Laitman Y, Rubinek T, Yeheskel A, Ben-Ami S, Kaufman B, Friedman E, Symon Z, Wolf I. Breast Cancer Res Treat. 144(1):123-31, 2014. (Abstract)(Full Text)

 

Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway. Dana Laor, Adi Cohen, Metsada Pasmanik-Chor, Varda Oron-Karni, Martin Kupiec and Ronit Weisman. Mol Cell Biol. 34(5):794-806, 2014. (Abstract)(Full Text)

 

HeatMapViewer: interactive display of 2D data in biology. Guy Yachdav, Maximilian Hecht, Metsada Pasmanik-Chor, Adva Yeheskel, Burkhard Rost. F1000Research, 3:48 (doi: 10.12688/f1000research.3-48.v1), 2014. (Abstract)(Full Text)

 

Vitamin D manipulates miR-181c, miR-20b and miR-15a in human umbilical vein endothelial cells exposed to a diabetic-like environment. Tali Zitman-Gal, Janice Green, Metsada Pasmanik-Chor, Eliezer Golan, Jacques Bernheim and Sydney Benchetrit. Cardiovascular Diabetology. 13(1):8, 2014. (Abstract)(Full Text)

 

T cell derived microvesicles induce mast cell production of IL-24: relevance to inflammatory skin diseases. Irit Shefler, Metsada Pasmanik-Chor, Dvora Kidron, Yoseph A. Mekori, Alon Y. Hershko, Journal of Allergy and Clinical Immunology, 133(1): 217-224, 2014. (Abstract)(Full Text)

 

2013

 

D538G Mutation in Estrogen Receptor-α: A Novel Mechanism for Acquired Endocrine Resistance in Breast Cancer.. Merenbakh-Lamin K, Ben-Baruch N, Yeheskel A, Dvir A, Soussan-Gutman L, Jeselsohn R, Yelensky R, Brown M, Miller VA, Sarid D, Rizel S, Klein B, Rubinek T, Wolf I. Cancer Res. 1;73(23):6856-64, 2013. (Abstract)(Full Text)

 

Genome wide expression profiling of human lymphoblastoid cell lines implicates integrin beta-3 in the mode of action of antidepressants. Keren Oved, Ayelet Morag, Metsada Pasmanik-Chor, Moshe Rehavi, Noam Shomron, David Gurwitz. Translational Psychiatry, 3, e313, 2013. (Abstract)(Full Text)

 

Gene expression profiles of ileal inflammatory bowel disease correlate with disease phenotype and advance understanding of its immunopathogenesis. S. Ben Shachar, H. Yanai, L. Baram, H. Elad, E. Meirovithz, A. Ofer, E. Brazowski, H. Tulchinsky, M. Pasmanik-Chor, I. Dotan. Inflammatory Bowel Disease, vol 19(12): 2509-21, 2013. (Abstract)

 

Microcephaly Thin Corpus Callosum Intellectual Disability syndrome caused by mutated TAF2. Shlomit Helman, Pola Smirin-Yosef, Ayelet Halevy, Metsada Pasmanik-Chor, Adva Yeheskel, Adi Har-Zahav, Rachel Straussberg, Mordechai Shohat, Lina Basel-Vanagaite, Pediatric Neurology, volume 49(6): 411-416.e1, 2013. (Abstract)(Full Text)

 

Biallelic SZT2 Mutations Cause Infantile Encephalopathy with Epilepsy and Dysmorphic Corpus Callosum. Basel-Vanagaite L, Hershkovitz T, Heyman E, Raspall-Chaure M, Kakar N, Smirin-Yosef P, Vila-Pueyo M, Kornreich L, Thiele H, Bode H, Lagovsky I, Dahary D, Haviv A, Hubshman MW, Pasmanik-Chor M, Nürnberg P, Gothelf D, Kubisch C, Shohat M, Macaya A, Borck G. Am J Hum Genet. Volume 93(3): 524–529, 2013. (Abstract)(Full Text)

 

Pax6 Regulates Gene Expression in the Vertebrate Lens through miR-204. Ohad Shaham, Karen Gueta, Eyal Mor, Pazit Oren-Giladi, Dina Grinberg, Qing Xie, Ales Cvekl, Noam Shomron, Noa Davis, Maya Keydar-Prizant, Shaul Raviv, Metsada Pasmanik-Chor, Rachel E. Bell, Carmit Levy, Raffaella Avellino, Sandro Banfi, Ivan Conte, and Ruth Ashery-Padan. PLoS Genetics, 9(3): e1003357. doi:10.1371/journal.pgen.1003357, 2013. (Abstract)(Full text)

 

Transcriptional profiling identifies genes induced by hepatocyte-derived extracellular matrix in metastatic human colorectal cancer cell lines. Isabel Zvibel, Adam Wagner, Metsada Pasmanik-Chor, Chen Varol, Varda Oron-Karni, Erwin M. Santo, Zamir Halpern, Revital Kariv. Clinical and Experimental Metastasis, 30(2): 189-200, 2013. (Abstract)(Full text)

 

MicroRNA Expression Signatures in Intraductal Papillary Mucinous Neoplasm of the Pancreas. Lubezky N, Lowenstein S, Ben-Haim M, Brazowsky E, Marmor S, Pasmanik-Chor M, Rechavi G, Klausner JM, Lahat G. Surgery, volume 153(5): 663–672, 2013. (Abstract)(Full text)

 

2012

 

Genome-wide transcriptomic variations of human lymphoblastoid cell lines: insights from pairwise gene-expression correlations. Marc Vincent, Keren Oved, Ayelet Morag, Metsada Pasmanik-Chor, Varda Oron-Karni, Noam Shomron, David Gurwitz. Pharmacogenomics, 13(16): 1893-1904, 2012. (Abstract)(Full text)

 

Vitamin D and Vascular Smooth Muscle Cells: Gene Modulation Following Exposure to a Diabetic-Like Environment. Tali Zitman-Gal, Janice Green, Metsada Pasmanik-Chor, Varda Oron-Karni, Jacques Bernheim, Sydney Benchetrit. journal of Diabetes Metabolism, 3(8): 218, 2012. (Abstract)(Full text)

 

Platinum-resistance in ovarian cancer cells is mediated by IL-6 secretion via the increased expression of its target cIAP-2. Sharon Cohen, Ilan Bruchim, Dror Graiver, Zoharia Evron, Varda Oron-Karni, Metsada Pasmanik-Chor, Ram Eitan, Joelle Bernheim, Hanoch Levavi, Ami Fishman, Eliezer Flescher. Journal of Molecular Medicine, DOI 10.1007/s00109-012-0946-4, 2012. (Abstract)(Full text)

 

Differential Expression of MicroRNAs between Aggressive and Non Aggressive Papillary Thyroid Carcinoma. Inon Buda, Gideon Bachar, Avital Gilam, Shira Modai, Yulia Strenov, Metsada Pasmanik-Chor, Raphael Feinmesser, Noam Shomron. Head Neck Oncol. 4(2): 52, 2012. (Abstract)(Full text)

 

Deficiency for the Ubiquitin Ligase UBE3B in a Blepharophimosis-Ptosis-Intellectual Disability Syndrome. Lina Basel-Vanagaite, Bruno Dallapiccola, Ramiro Ramirez-Solis, Alexandra Segref, Holger Thiele, Andrew Edwards, Mark J Arends, Xavier Miró, Jacqueline K White, Julie Désir, Marc Abramowicz, Maria Lisa Dentici, Francesca Lepri, Kay Hofmann, Adi Har Zahav, Edward Ryder, Jeanne Estabel, Anna-Karin B Gerdin, Christine Podrini, Neil J Ingham, Janine Altmüller, Gudrun Nürnberg, Peter Frommolt, Sonia Abdelhak, Metsada Pasmanik-Chor, Osnat Konen, Richard I. Kelley, Mordechai Shohat, Peter Nürnberg, Jonathan Flint, Karen P Steel, Thorsten Hoppe, Christian Kubisch, David J Adams & Guntram Borck. Am J Hum Genet. 91: 998-1010, 2012. (Abstract)(Full text)

 

Genome-wide miRNA expression profling of human lymphoblastoid cell lines identifes tentative SSRIs response biomarkers. Keren Oved, Ayelet Morag, Metsada Pasmanik-Chor, Varda Oron-Karni, Noam Shomron, Moshe Rehavi, Julia C Stngl, David Gurwitz. Pharmacogenomics, Future Medicine 13(10): 1129-1139, 2012. (Abstract)(Full text)

 

Expression pattern of SVEP1 alternatively-spliced forms. Glait-Santar C, Pasmanik-Chor M, Benayahu D. Gene 15; 505(1): 137-45, 2012. (Abstract)(Full text)

 

Renal failure is associated with driving of gene expression towards cardiac hypertrophy and reduced mitochondrial activity. Michal Entin-Meer, Metsada Pasmanik-Chor, Jeremy Ben-Shoshan, Sofia Maysel-Auslender, Pavel Goryainov, Varda Oron-Karni, Jonathan Semo, Einat Herzberg, Gad Keren. Journal of Clinical & Experimental Cardiology, 3: 184. doi:10.4172/2155-9880.1000184, 2012. (Full text)

 

Downregulation of miR-31, miR-155, AND miR-564 in chronic myeloid leukemia cells. Hershkovitz Rokah O., Granot G., Ovcharenko A., Modai S., Pasmanik-Chor M., Toren A, Shomron N., Shpilberg O. PLoS ONE 7(4): e35501. doi:10.1371/journal.pone.0035501, 2012. (Abstract)(Full text)

 

The MARVEL transmembrane domain of Occludin mediates oligomerization and targeting to the basolateral surface in epithelia. Yakey Yaffe, Jeanne Shepshelovitch, Adva Yeheskel, Hedva Shmerling, Joanna M Kwiatek, Katharina Gaus, Metsada Pasmanik-Chor, and Koret Hirschberg. Journal of Cell Science, 125: 3545-3556, 2012. (Abstract)(Full text)

 

The metastatic microenvironment: Brain-derived soluble factors alter the malignant phenotype of cutaneous and brain- metastasizing melanoma cells. Klein, A, Sagi-Assif, O, Izraely, S, Meshel, T, Pasmanik-Chor, M, Nahmias, C, Couraud, PO, Erez, N, S.B. Hoon, D, Witz, I. International Journal of Cancer, 1;131(11): 2509-18, 2012. (Abstract)(Full text)

 

Tetraspanins stimulate protein synthesis in myeloma cell lines. Victoria Zismanov, Liat Drucker, Shelly Tartakover Matalon, Metsada Pasmanik-Chor, and Michael Lishner. Journal of Cellular Biochemistry, 113(7): 2500-2510, 2012. (Abstract)(Full text)

 

Mechanisms Regulating the Secretion of the Promalignancy Chemokine CCL5 by Breast Tumor Cells: CCL5's 40s Loop and Intracellular Glycosaminoglycans. Soria G, Lebel-Haziv Y, Ehrlich M, Meshel T, Suez A, Avezov E, Rozenberg P, Ben-Baruch A. Neoplasia 14(1): 1-19, 2012. (Abstract)(Full Text)

 

Molecular profiling of functional interactions between pre-osteoblastic and breast carcinoma cells. Chen Glait-Santar, Metsada Pasmanik-Chor, Varda Oron-Karni, Benayahu Dafna. Genes to Cells, volume 17(4): 302–315, 2012. (Abstract) (Full text)

 

Transient Infantile Hypertriglyceridemia, Fatty Liver, and Hepatic Fibrosis Caused by Mutated GPD1, Encoding Glycerol-3-Phosphate Dehydrogenase 1. Lina Basel-Vanagaite, Noam Zevit, Adi Har Zahav, Liang Guo, Saj Parathath, Metsada Pasmanik-Chor, Adam D.McIntyre, Jian Wang, Adi Albin-Kaplanski, Corina Hartman, Daphna Marom, Avraham Zeharia, Abir Badir, Oded Shoerman, Amos J. Simon, Gideon Rechavi, Mordechai Shohat, Robert A. Hegele, Edward A. Fisher, Raanan Shamir , The American Journal of Human Genetics, 13;90(1): 49-60, 2012. (Abstract) (Full text)

 

Insulin-like growth factor-I receptor (IGF-IR) translocates to the nucleus and autoregulates IGF-IR gene expression in breast cancer cells. Rive Sarfstein, Metsada Pasmanik-Chor, Adva Yeheskel, Liat Edry, Noam Shomron, Naama Warman, Efrat Wertheimer, Sharon Maor, Lea Shochat and Haim Werner. J Biol Chem, 20;287(4):2766-76, 2012. (Abstract) (Full Text)

 

Hormone-dependent placental manipulation of breast cancer cell migration. Epstein-Shochet G, Tartakover-Matalon S, Drucker L, Pomeranz M, Fishman A, Rashid G, Oron-Karni V, Pasmanik-Chor M and Lishner M. Hum. Reprod. 27 (1): 73-88, 2012. doi: 10.1093/humrep/der365 (Abstract)(Full text)

 

2011

 

The Metastatic Microenvironment. Brain Residing Melanoma Metastasis and Dormant Micro-Metastasis. Sivan Izraeli, Orit Sagi-Assif, Anat Klein, Tzipi Meshel, Galia Tzarfaty, Metsada Pasmanik-Chor, Clara Nahmias, Pierre-Olivier Couraud, Eugene Aten, Joseph Bryant, Dave Hoon and Isaac Witz. International Journal of Cancer, DOI: 10.1002/ijc.27324, 2011 (Abstact)(Full text)

 

The Type III Effector HsvG of the Gall-Forming Pantoea agglomerans Mediates Expression of the Host Gene HSVGT. Gal Nissan, Shulamit Manulis-Sasson, Laura Chlupowicz, Doron Teper, Adva Yeheskel, Metsada Pasmanik-Chor, Guido Sessa, and Isaac Barash. Molecular Plant-Microbe Interactions, DOI: 10.1094/MPMI-06-11-0173, 2011 (Abstract)(Full text)

 

Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro. Holger A. Russ. Elad Sintov, Leeat Anker-Kitai, Orr Friedman, Ayelet Lenz, Ginat Toren, Chen Farhy, Metsada Pasmanik-Chor, Varda Oron-Karni, Philippe Ravassard and Shimon Efrat. PLoS One 6(9): e25566, doi:10.1371/journal.pone.0025566 (Abstract)(Full text)

 

The enigma of the E326K mutation in acid beta-glucocerebrosidase. Mia Horowitz, Metsada Pasmanik-Chor, Idit Ron, Edwin H Kolodny Molecular Genetics and Metabolism, volume 104(1-2): 35-38, 2011. (Abstract)(Full text)

 

Global changes in gene expression of grapefruit peel tissue in response to the yeast biocontrol agent Metschnikowia fructicola. Hershkovitz, Vera; Ben-Dayan, Clarita; Raphael, Ginat; Pasmanik-Chor, Metsada; Liu, Jia; Belausov, Eduard; Aly, Radi; Wisniewski, Michael E.; Droby, Samir. Molecular Plant Pathology. doi: 10.1111/j.1364-3703.2011.00750.x., 2011. (Abstract)(Full text)

 

Effects of IKAP/hELP1 deficiency on gene expression in differentiating neuroblastoma cells: implications for Familial Dysautonomia. Rachel Cohen-Kupiec, Metsada Pasmanik-Chor, Varda Oron-Karni and Miguel Weil. PLoS One, 6(4): e19147, 2011. (Abstract)(Full text)

 

Multiple congenital anomalies-hypotonia-seizures syndrome is caused by a mutation in PIGN. Gal Maydan, Iris Noyman, Adi Har-Zahav, Ziva Ben Neriah, Metsada Pasmanik-Chor, Adva Yeheskel, Adi Albin-Kaplanski, Idit Maya, Nurit Magal, Efrat Birk, Amos J Simon, Ayelet Halevy, Gideon Rechavi, Mordechai Shohat, Rachel Straussberg, Lina Basel-Vanagaite. J Med Genet DOI:10.1136/jmg.2010.087114, 2011. (Abstract)(Full text)

 

CDH3-Related Syndromes: Report on a New Mutation and Overview of the Genotype-Phenotype Correlations. Basel-Vanagaite, M. Pasmanik-Chor, R. Lurie, A. Yeheskel, K.W. Kjaer. Mol Syndromol DOI: 10.1159/000327156, 2011. (Abstract)(Full text)

 

Genome-wide expression profiling of human lymphoblastoid cell lines identifies CHL1 as putative SSRI antidepressants response biomarker. Ayelet Morag, Metsada Pasmanik-Chor, Varda Oron-Karni, Moshe Rehavi, Julia C Stingl, and David Gurwitz. Pharmacogenomics. 12(2): 171-184, 2011. (Abstract)(Full text)

 

2010

 

SOBP is mutated in syndromic and nonsyndromic intellectual disability and is highly expressed in the brain limbic system. Birk E, Har-Zahav A, Manchini C, Pasmarnik-Chor M, Korenreich L, Walsh CA., Noben-Trauth K, Albin A, Simon AJ, Collaux L, Morad Y, Reinshtein L, Tischfield D, Wang P, Magal N, Maya I, Shoshani N, Rehavi G, Gothelf D, Shohat M, Basel-Vanagaite L. Am J Hum Genet. 87(5): 694-700, 2010. (Abstract)(Full text).

 

Staphylococcus aureus NrdH-redoxin is a reductant of the class Ib ribonucleotide reductase. Rabinovitch I, Yanku M, Yeheskel A, Cohen G, Borovok I, Aharonowitz Y. J Bacteriol. 192(19): 4963-72, 2010. (Abstract)(Abstract)

 

Genetic and antigenic characterization of sigma C protein from avian reovirus. Goldenberg D, Pasmanik-Chor M, Pirak M, Kass N, Lublin A, Yeheskel A, Heller D, Pitcovski J. Avian Pathol. 39(3): 189-99, 2010. (Abstract)(Full Text)

 

DOC2B, C2 domains, and calcium: A tale of intricate interactions. Friedrich R, Yeheskel A, Ashery U. Mol Neurobiol. 41(1): 42-51, 2010. (Abstract)(Full text)

 

Endothelial pro-atherosclerotic response to extracellular diabetic-like environment: Possible role of thioredoxin-interacting protein. Zitman-Gal T, Green J, Pasmanik-Chor M, Oron-Karni V, Bernheim J. Nephrol Dial Transplant. 25(7): 2141-9, 2010. (Abstract)(Full Text)

 

Transcription factor E2F1 is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene. Schayek H, Bentov I, Rotem I, Pasmanik-Chor M, Ginsberg D, Plymate SR, Werner H. Growth Horm IGF Res. 20(1): 68-72, 2010. (Abstract)(Full Text)

 

2009

 

Gene-expression-based analysis of local and metastatic neuroblastoma variants reveals a set of genes associated with tumor progression in neuroblastoma patients. Nevo I, Oberthuer A, Botzer E, Sagi-Assif O, Maman S, Pasmanik-Chor M, Kariv N, Fischer M, Yron I, Witz IP. Int J Cancer. 126(7): 1570-81, 2009. (Abstract)(Full Text)

 

The gene road to royalty-differential expression of hydroxylating genes in the mandibular glands of the honeybee. Malka O, Karunker I, Yeheskel A, Morin S, Hefetz A. FEBS J. 276(19): 5481-90, 2009. (Abstract)(Full Text)

 

2008

 

Short-term exercise training induces cardiac protection through molecular stimulation of the remodeled left ventricle. Dayan Anat, Pasmanik-Chor Metsada, Jacob Jasmine, Scheinowitz Mickey. Journal of Molecular and Cellular Cardiology, Volume 44, Issue 4, Page 769, 2008 (Abstract)

 

Autosomal recessive ichthyosis with hypotrichosis syndrome: further delineation of the phenotype. Avrahami L, Maas S, Pasmanik-Chor M, Rainshtein L, Magal N, Smitt J, van Marle J, Shohat M, Basel-Vanagaite L. Clin Genet. 74(1): 47-53, 2008. (Abstract)(Full Text)

 

Attenuation of very virulent infectious bursal disease virus and comparison of full sequences of virulent and attenuated strains. Lazarus D, Pasmanik-Chor M, Gutter B, Gallili G, Barbakov M, Krispel S, Pitcovski J. Avian Pathol. 37(2): 151-9, 2008. (Abstract)(Full text)

 

E-selectin regulates gene expression in metastatic colorectal carcinoma cells and enhances HMGB1 release. Aychek T, Miller K, Sagi-Assif O, Levy-Nissenbaum O, Israeli-Amit M, Pasmanik-Chor M, Jacob-Hirsch J, Amariglio N, Rechavi G, Witz IP. Int J Cancer. 123(8): 1741-50, 2008. (Abstract)(Full Text)

 

2007

 

Autosomal recessive ichthyosis with hypotrichosis caused by a mutation in ST14, encoding type II transmembrane serine protease matriptase. Basel-Vanagaite L, Attia R, Ishida-Yamamoto A, Rainshtein L, Ben Amitai D, Lurie R, Pasmanik-Chor M, Indelman M, Zvulunov A, Saban S, Magal N, Sprecher E, Shohat M. Am J Hum Genet. 80(3): 467–477, 2007. (Abstract)(Full Text)

 

 

2006

 

Mutated nup62 causes autosomal recessive infantile bilateral striatal necrosis. Basel-Vanagaite L, Muncher L, Straussberg R, Pasmanik-Chor M, Yahav M, Rainshtein L, Walsh CA, Magal N, Taub E, Drasinover V, Shalev H, Attia R, Rechavi G, Simon AJ, Shohat M. Ann Neurol. 60(2): 214-22, 2006. (Abstract)(Full Text)

 

Recycling to the plasma membrane is delayed in EHD1 knockout mice. Rapaport D, Auerbach W, Naslavsky N, Pasmanik-Chor M, Galperin E, Fein A, Caplan S, Joyner AL, Horowitz M. Traffic. 7(1): 52-60, 2006. (Abstract)(Full Text)

 

2005 and before

 

Use of fluorescent substrates for characterization of Gaucher disease mutations. Ron I, Dagan A, Gatt S, Pasmanik-Chor M, Horowitz M. Blood Cells Mol Dis. 35(1):57-65, 2005. (Abstract)(Full Text)

 

Prevalence of glucocerebrosidase mutations in the Israeli Ashkenazi Jewish population. Horowitz M, Pasmanik-Chor M, Borochowitz Z, Falik-Zaccai T, Heldmann K, Carmi R, Parvari R, Beit-Or H, Goldman B, Peleg L, Levy-Lahad E, Renbaum P, Legum S, Shomrat R, Yeger H, Benbenisti D, Navon R, Dror V, Shohat M, Magal N, Navot N, Eyal N. Hum Mutat. 1998;12(4):240-4. Erratum in: Hum Mutat 1999;13(3):255. (Abstract)(Full text)

 

Intracellular degradation of fluorescent glycolipids by lysosomal enzymes and their activators. Madar-Shapiro L, Pasmanik-Chor M, Dinur T, Dagan A, Gatt S, Horowitz M. J Inherit Metab Dis. 1999 Jun;22(5):623-37. (Abstract)

 

EHD1--an EH-domain-containing protein with a specific expression pattern. Mintz L, Galperin E, Pasmanik-Chor M, Tulzinsky S, Bromberg Y, Kozak CA, Joyner A, Fein A, Horowitz M. Genomics. 1999 Jul 1;59(1):66-76. (Abstract)(Full text)

 

Importance of splicing for prosaposin sorting. Madar-Shapiro L, Pasmanik-Chor M, Vaccaro AM, Dinur T, Dagan A, Gatt S, Horowitz M. Biochem J. 1999 Feb 1;337 ( Pt 3):433-43. (Abstract)

 

Expression of mutated glucocerebrosidase alleles in human cells. Pasmanik-Chor M, Madar-Shapiro L, Stein EO, Aerts H, Gatt S, Horowitz M. Hum Mol Genet. 1997 Jun;6(6):887-95. (Abstract)(Full text)

 

Overexpression of human glucocerebrosidase containing different-sized leaders. Pasmanik-Chor M, Elroy-Stein O, Aerts H, Agmon V, Gatt S, Horowitz M. Biochem J. 1996 Jul 1;317 ( Pt 1):81-8. (Abstract)

 

The glucocerebrosidase D409H mutation in Gaucher disease. Pasmanik-Chor M, Laadan S, Elroy-Stein O, Zimran A, Abrahamov A, Gatt S, Horowitz M. Biochem Mol Med. 1996 Dec;59(2):125-33. (Abstract)

 

Dexamethasone inhibition of prostaglandin production in human term placental cells is protein and ribonucleic acid synthesis dependent. Pasmanik M, Izhar M, Zolti M, Shemesh M. Endocrinology. 1991 Apr;128(4):2058-64. (Abstract)

 

Dexamethasone inhibition of cyclooxygenase expression in bovine term placenta. Izhar M, Pasmanik M, Marcus S, Shemesh M. Prostaglandins. 1992 Mar;43(3):239-54. (Abstract)

 

Bovine placental progesterone synthesis: comparison of first and second trimesters of gestation. Izhar M, Pasmanik M, Shemesh M. Biol Reprod. 1992 May;46(5):846-52. (Abstract)

 

Regulation of steroidogenesis in the bovine placenta. Shemesh M, Izhar M, Pasmanik M, Shore LS. J Physiol Pharmacol. 1992 Dec;43(4 Suppl 1):153-63. (Abstract)

 

Aromatization and estrogen action in brain. Callard G, Schlinger B, Pasmanik M, Corina K. Prog Clin Biol Res. 1990;342:105-11.

 

Nonmammalian vertebrate models in studies of brain-steroid interaction. Callard G, Schlinger B, Pasmanik M. J Exp Zool Suppl. 1990;4:6-16. Review. (Abstract)

 

A high abundance androgen receptor in goldfish brain: characteristics and seasonal changes. Pasmanik M, Callard GV. Endocrinology. 1988 Aug;123(2):1162-71. (Abstract)

 

In vivo steroid regulation of aromatase and 5 alpha-reductase in goldfish brain and pituitary. Pasmanik M, Schlinger BA, Callard GV. Gen Comp Endocrinol. 1988 Jul;71(1):175-82. (Abstract)

 

Changes in brain aromatase and 5 alpha-reductase activities correlate significantly with seasonal reproductive cycles in goldfish (Carassius auratus). Pasmanik M, Callard GV. Endocrinology. 1988 Apr;122(4):1349-56.. (Abstract)

 

The role of estrogen as a parahormone in brain and pituitary. Callard GV, Pasmanik M. Steroids. 1987 Oct-Dec;50(4-6):475-93. Review. (Abstract)

 

Characteristics of a testosterone-estradiol binding globulin (TEBG) in goldfish serum. Pasmanik M, Callard G. Biol Reprod. 1986 Nov;35(4):838-45. (Abstract)

 

Aromatase and 5 alpha-reductase in the teleost brain, spinal cord, and pituitary gland. Pasmanik M, Callard GV. Gen Comp Endocrinol. 1985 Nov;60(2):244-51. (Abstract)

 

Acknowledgments

 

Induced neural differentiation of human mesenchymal stem cells affects lipid metabolism pathways. Pnina Green, Inna Kan, Ronit Mesilati-Stahy, Nurit Argov-Argaman, Daniel Offen. bioRxiv preprint doi: https://doi.org/10.1101/2021.01.17.427010, 2021 (Full Text)

 

The dehydrogenase region of the NADPH oxidase component Nox2 acts as a protein disulfide isomerase (PDI) resembling PDIA3 with a role in the binding of the activator protein p67 (phox.).. Front Chem. 2015 Feb 4;3:3.. Bechor E, Dahan I, Fradin T, Berdichevsky Y, Zahavi A, Federman Gross A, Rafalowski M, Pick E.. (Full Text)

 

The effects of telomere shortening on cancer cells: A network model of proteomic and microRNA analysis. Genomics 105 (1): 5–16, 2015. O. Uziel, N. Yosef, R. Sharan, E. Ruppin, M. Kupiec, M. Kushnir, E. Beery, T. Cohen-Diker, J. Nordenberg, M. Lahav. (Full Text)

 

A novel MKRN3 missense mutation causing familial precocious puberty. Hum Reprod. 2014 Dec;29(12):2838-43. de Vries L, Gat-Yablonski G, Dror N, Singer A, Phillip M. (Abstract) (Full Text)

 

ADNP, A MAJOR AUTISM MUTATED GENE IS DIFFERENTIALY DISTRIBUTED (AGE AND SEX) IN THE SONGBIRD BRAIN. the Israeli society for neuroscience (ISFN) conference in Eilat, 2014. Hacohen Kleiman G, Barnea A, Gozes I (Abstract)

 

Computational Thinking in Life Science Education.PLoS Computational Biology, 10(11): e1003897, Nov. 2014. Amir Rubinstein and Benny Chor (Full Text)

 

A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency. Hum Genet. 127(6):721-9 (2010). Liat Ashkenazi-Hoffnung, Yael Lebenthal, Alexander W. Wyatt, Nicola K. Ragge, Sumito Dateki, Maki Fukami, Tsutomu Ogata, Moshe Phillip and Galia Gat-Yablonski (Full Text)

 

Expander: from expression microarrays to networks and functions. Nature Protocols 5, 303-322 (2010). Igor Ulitsky, Adi Maron-Katz, Seagull Shavit, Dorit Sagir, Chaim Linhart, Ran Elkon, Amos Tanay, Roded Sharan, Yosef Shiloh & Ron Shamir (Full Text)

 

Activation of Mast Cells by Trimeric G Protein Gi3; Coupling to the A3 Adenosine Receptor Directly and upon T Cell Contact. J Immunol 184, 3677-3688 (2010). Dana Baram, Ornit Dekel, Yoseph A. Makori and Ronit Sagi-Eisenberg. (Full Text)

 

Innexin genes and gap junction proteins in the locust frontal ganglion. Insect Biochemistry and Molecular Biology 39 (3): 224–33 (2009). Sarit Anava, David Rand, Yael Zilberstein, Amir Ayali. (Full Text)

 

Genetic code symmetry and efficient design of GC-constrained coding sequences. Bioinformatics 23 (2): e57-e63 (2007). Matan Gavish, Amnon Peled and Benny Chor. (Full Text)

 

Minireview: CAMTAs: Calmodulin-binding transcription activators from plants to human. FEBS Letters 581(21): 3893-3898 (2007). Aliza Finkler, Ruth Ashery-Padan, Hillel Fromm. (Full text)

 

Maximum likelihood of evolutionary trees: hardness and approximation. Bioinformatics vol 21, suppl 1: i97-i106 (2005). Benny Chor and Tamir Tuller. (Abstract)