Octet® R4 BLI
For enquiries, please contact - Dr. Karin Smorodinsky-Atias
The information provided in this section is taken from the "Octet® R4, 4-Channel Protein Analysis System" Sartorius product website.
Bio-Layer Interferometry (BLI)
BLI is an optical technology that measures the changes in interference pattern between light waves.
Sartorius’s Octet® BLI platforms measure light interference originating from the tip of the biosensor surface where light wavelengths are made to reflect from two layers:
a biocompatible layer at the end of the biosensor surface and an internal reference layer.
Applications
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Binding Kinetics and Affinity
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Concentration analysis
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Potency analysis
Requirements
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Octet biosensors with the required surface modification
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Means to attach one of the interacting partners to the biosensor
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A black 96-well plate from Greiner (cat. #655209)
Advantages
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Real time measurements
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Fast and easy method
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Samples may be recovered
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High throughput
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Biosensors can be reused
