Operetta CLS
Location - Britannia 104
For enquiries, please contact - Dr. Alex Barbul
The information provided in this section is taken from Operretta instrument webpage by Revvity.
Common Applications:
The Operetta CLS is a versatile platform with a wide range of applications in cellular biology and drug discovery:
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Phenotypic Screening: Identify and characterize subtle cellular changes in response to drug compounds, genetic perturbations, or disease models.
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Live-Cell Assays: Study dynamic processes like migration and invasion assays, proliferation, apoptosis, endocytosis, and signaling pathways over time, monitor cell calcium, track cardiomyocyte beating, colony formation, monitoring drug-induced effects, internalization assays, object tracking.
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Fixed-Cell Assays: Analise cellular structures, protein localization, and molecular interactions in fixed samples.
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3D Cell Culture Imaging: Gain deeper insights into more physiologically relevant models like spheroids, organoids, and tissue sections, capturing volumetric data.
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Drug Discovery and Development: From target identification and validation to product development and workflow optimization and toxicology studies.
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Advanced Assays: Perform FRET (Förster Resonance Energy Transfer) for studying protein-protein interactions, or ratiometric imaging for tracking ion fluxes.
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Infectious Diseases: Characterize pathogen-host interactions, determine infection rates, and analyze host-cell phenotypes.
