Research area: Neuroimmunology, Neurodegeneration.
Current Research Topics: The role of glia cells during central nervous system inflammation using models of stroke, Alzheimer's disease, Parkinson’s disease and multiple sclerosis.
Methods & Techniques: Neurobiology,Immunology, Cell biology, Molecular biology, Histology.
The research in the laboratory focus on glial-neuronal cell interactions to clarify their role in neurological diseases, both in culture and in animal models of Parkinson’s Disease, and Alzheimer’. The laboratory combines approaches such as molecular biology, immunological approaches, histological approach and behavioral approach to shed light on the genes and proteins involved in glial cell function, in particular microglia and astrocyte in neurodegenerative diseases. The laboratory developed novel approaches to isolate adult glia from mice and to investigate their genetic and proteins profile that relate to pathological condition. Research focus on the link between inflammation to neurodegenerative diseases and the laboratory develop and investigate new therapeutic approach to treat AD and has several approved patents.